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Adrenergic beta-1 Receptor Antagonists: classification

Beta-1-selective blockers preferentially antagonize cardiac and renal beta-1 receptors. Selectivity is relative and diminishes as dose increases.

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very high

Adrenergic beta-1 Receptor Antagonists: mechanism

Beta-1-selective blockers preferentially antagonize cardiac and renal beta-1 receptors. Selectivity is relative and diminishes as dose increases.

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very high

Adrenergic beta-1 Receptor Antagonists: safety

Bradycardia, hypotension, fatigue and conduction block. Pulmonary risk is lower than with nonselective agents but is not absent.

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Adrenergic beta-1 Receptor Antagonists: classification

Representative beta-1-selective blockers include metoprolol, atenolol, bisoprolol, esmolol and nebivolol. Selectivity is dose-dependent rather than absolute.

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high

Adrenergic beta-1 Receptor Antagonists: mechanism

Beta-1-selective blockers preferentially antagonize cardiac and renal beta-1 receptors. Selectivity is relative and diminishes as dose increases.

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high

Adrenergic beta-2 Receptor Antagonists: classification

Selective beta-2 antagonists do not form a major routine therapeutic drug class. Beta-2 blockade is encountered chiefly as part of nonselective beta-blocker pharmacology.

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