Adrenergic alpha-1 Receptor Antagonists
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AMD:CLASS:00999
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Non-uroselective agents include prazosin, doxazosin and terazosin.
Blockade reduces Gq-mediated smooth-muscle contraction, causing vasodilation and relaxation of prostate and bladder-neck smooth muscle.
Dizziness, postural hypotension, syncope, headache and nasal congestion may occur.
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