Adrenergic beta-3 Receptor Agonists
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AMD:CLASS:00996
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Mirabegron and vibegron are the principal therapeutic beta-3 agonists for overactive bladder.
Beta-3 activation increases cyclic AMP and relaxes detrusor smooth muscle during the storage phase of the fill-void cycle, increasing bladder capacity…
Hypertension, headache, urinary tract infection, nasopharyngitis, tachycardia and urinary retention may occur.
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