Adrenergic beta-1 Receptor Agonists
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AMD:CLASS:00994
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Dobutamine is beta-1 predominant but also has weaker beta-2 and alpha-1 actions.
Beta-1 receptors couple to Gs, increasing cyclic AMP and calcium handling in cardiomyocytes.
Tachycardia, ectopic beats, atrial or ventricular arrhythmias, angina and blood-pressure changes may occur.
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