Adrenergic alpha-2 Receptor Agonists
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AMD:CLASS:00992
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Important subgroups include antihypertensive or ADHD agents such as clonidine and guanfacine, methyldopa used particularly in pregnancy, sedative dexm…
Alpha-2 receptors couple to Gi, reducing cyclic AMP and norepinephrine release.
Sedation, dry mouth, bradycardia, hypotension and constipation may occur.
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