Adrenergic alpha-1 Receptor Agonists
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AMD:CLASS:00991
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Systemic examples include phenylephrine and midodrine.
Alpha-1 receptors couple through Gq to phospholipase C, inositol trisphosphate and increased intracellular calcium, producing smooth-muscle contractio…
Hypertension, reflex bradycardia, headache, urinary retention, piloerection and tissue ischaemia can occur.
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