Angiotensin II Type 1 Receptor Blockers
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AMD:CLASS:00867
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AT1 receptor blockers selectively prevent angiotensin II signalling at the AT1 receptor.
AT1 blockade reduces vasoconstriction, aldosterone release, sympathetic facilitation and sodium retention while leaving ACE-mediated bradykinin breakd…
Hyperkalaemia, hypotension and a rise in creatinine are central concerns; cough is much less characteristic than with ACE inhibition.
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