Peripherally Acting Antiadrenergic Agents
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AMD:CLASS:00680
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The historical group includes reserpine, which blocks vesicular monoamine transport, and guanethidine, which enters adrenergic terminals and inhibits …
Reserpine prevents vesicular storage and gradually depletes norepinephrine, dopamine and serotonin.
Marked postural hypotension, diarrhoea, nasal congestion, sexual dysfunction and fluid retention can occur.
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