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Loop Diuretics

Latest published update: 30 Jul 2026
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Loop Diuretics: classification

Inhibit the Na-K-2Cl cotransporter in the thick ascending limb of the loop of Henle, collapsing the medullary concentration gradient and producing pot…

Loop Diuretics: safety

Hypokalaemic metabolic alkalosis, hyponatraemia, hypomagnesaemia, volume depletion, hyperuricaemia and ototoxicity. Most are sulfonamides; Ethacrynic …

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