Loop Diuretics
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AMD:CLASS:00575
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Inhibit the Na-K-2Cl cotransporter in the thick ascending limb of the loop of Henle, collapsing the medullary concentration gradient and producing pot…
Furosemide, Bumetanide, Torsemide and Ethacrynic acid are important examples.
Hypokalaemic metabolic alkalosis, hyponatraemia, hypomagnesaemia, volume depletion, hyperuricaemia and ototoxicity. Most are sulfonamides; Ethacrynic …
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