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Diuretics

Latest published update: 30 Jul 2026
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Diuretics: classification

Diuretics increase renal sodium and water excretion through nephron-site-specific mechanisms. Their clinical effect depends on delivered drug, kidney …

Diuretics: mechanism

Major groups include carbonic-anhydrase inhibitors in the proximal tubule, loop diuretics in the thick ascending limb, thiazides in the distal convolu…

Diuretics: safety

Volume depletion, hypotension, kidney-function deterioration and sodium, potassium, magnesium, calcium or acid–base disturbances vary by class.

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